fidzu : computers

Bruce66423 shares a report from the Los Angeles Times: Tattoo ink doesn't just sit inertly in the skin. New research shows it moves rapidly into the lymphatic system, where it can persist for months, kill immune cells, and even disrupt how the body responds to vaccines. Scientists in Switzerland used a mouse model to trace what happens after tattooing. Pigments drained into nearby lymph nodes within minutes and continued to accumulate for two months, triggering immune-cell death and sustained inflammation. The ink also weakened the antibody response to Pfizer Inc. and BioNTech SE's COVID vaccine when the shot was administered in tattooed skin. In contrast, the same inflammation appeared to boost responses to an inactivated flu vaccine. "This work represents the most extensive study to date regarding the effect of tattoo ink on the immune response and raises serious health concerns associated with the tattooing practice," the researchers said. "Our work underscores the need for further research to inform public health policies and regulatory frameworks regarding the safety of tattoo inks." The findings have been published in the journal Proceedings of the National Academy of Sciences.

Read more of this story at Slashdot.

03 Dec 2025 7:07am GMT

Anthropic has made its first acquisition by buying Bun, the engine behind its fast-growing Claude Code agent. The move strengthens Anthropic's push into enterprise developer tooling as it scales Claude Code with major backers like Microsoft, Nvidia, Amazon, and Google. Adweek reports: Claude Code is a coding agent that lets developers write, debug and interpret code through natural-language instructions. Claude Code had already hit $1 billion in revenue six months since its public debut in May, according to a LinkedIn post from Anthropic's chief product officer, Mike Krieger. The coding agent continues to barrel toward scale with customers like Netflix, Spotify, and Salesforce. Further reading: Meet Bun, a Speedy New JavaScript Runtime

Read more of this story at Slashdot.

03 Dec 2025 5:05am GMT

An anonymous reader quotes a report from the New York Times: The San Francisco city attorney filed on Tuesday the nation's first government lawsuit against food manufacturers over ultraprocessed fare (source may be paywalled; alternative source), arguing that cities and counties have been burdened with the costs of treating diseases that stem from the companies' products. David Chiu, the city attorney, sued 10 corporations that make some of the country's most popular food and drinks. Ultraprocessed products now comprise 70 percent of the American food supply and fill grocery store shelves with a kaleidoscope of colorful packages. Think Slim Jim meat sticks and Cool Ranch Doritos. But also aisles of breads, sauces and granola bars marketed as natural or healthy. It is a rare issue on which the liberal leaders in San Francisco City Hall are fully aligned with the Trump administration, which has targeted ultraprocessed foods as part of its Make America Healthy Again mantra. Mr. Chiu's lawsuit, which was filed in San Francisco Superior Court on behalf of the State of California, seeks unspecified damages for the costs that local governments bear for treating residents whose health has been harmed by ultraprocessed food. The city accuses the companies of "unfair and deceptive acts" in how they market and sell their foods, arguing that such practices violate the state's Unfair Competition Law and public nuisance statute. The city also argues the companies knew that their food made people sick but sold it anyway.

Read more of this story at Slashdot.

03 Dec 2025 3:03am GMT

The last Trump official in the position left amid allegations of petty revenge.

02 Dec 2025 11:17pm GMT

From the outside, China's Zhuque-3 rocket looks like a clone of SpaceX's Falcon 9.

02 Dec 2025 11:04pm GMT

Three years after Google sounded alarm bells over ChatGPT, the tables have turned.

02 Dec 2025 10:42pm GMT

The FreeBSD team has released FreeBSD 15.0, and with it come several major changes, one of which you will surely want to know more about if you're a FreeBSD user. Since this change will eventually drastically change the way you use FreeBSD, we should get right into it. Up until now, a full, system-wide update for FreeBSD - as in, updating both the base operating system as well as any packages you have installed on top of it - would use two separate tools: freebsd-update and the pkg package manager. You used the former to update the base operating system, which was installed as file sets, and the latter to update everything you had installed on top of it in the form of packages. With FreeBSD 15.0, this is starting to change. Instead of using two separate tools, in 15.0 you can opt to deprecate freebsd-update and file sets, and rely entirely on pkg for updating both the base operating system as well as any packages you have installed, because with this new method, the base system moves from file sets to packages. When installing FreeBSD 15.0, the installer will ask you to choose between the old method, or the new pkg-only method. Packages (pkgbase / New Method): The base system is installed as a set of packages from the "FreeBSD-base" repository. Systems installed this way are managed entirely using the pkg(8) tool. This method is used by default for all VM images and images published in public clouds. In FreeBSD 15.0, pkgbase is offered as a technology preview, but it is expected to become the standard method for managing base system installations and upgrades in future releases. ↫ FreeBSD 15.0 release announcement As the release announcement notes, the net method is optional in FreeBSD 15 and will remain optional during the entire 15.x release cycle, but the plan is to deprecate freebsd-update and file sets entirely in FreeBSD 16.0. If you have an existing installation you wish to convert to using pkgbase, there's a tool called pkgbasify to do just that. It's sponsored by the FreeBSD Foundation, so it's not some random script. Of course, there's way more in this release than just pkgbase. Of note is that the 32bit platforms i386, armv6, and 32-bit powerpc have been retired, but of course, 32bit code will continue to run on their 64bit counterparts. FreeBSD 15.0 also brings a native inotify implementation, a ton of improvements to the audio components, improved Intel Wi-Fi drivers, and so, so much more.

02 Dec 2025 8:34pm GMT

On its own, the title of this post is just a true piece of trivia, verifiable with the built-in subst tool (among other methods). Here's an example creating the drive +:\ as an alias for a directory at C:\foo: The +:\ drive then works as normal (at least in cmd.exe, this will be discussed more later): However, understanding why it's true elucidates a lot about how Windows works under the hood, and turns up a few curious behaviors. ↫ Ryan Liptak Fascinating doesn't even begin to describe this article, but at the same time, it also makes me wonder at what point maintaining this drive letter charade becomes too burdensome, clunky, and complex. Internally, Windows NT does not use drive letters at all, but for the sake of backwards compatibility and to give the user what they expect, a whole set of abstractions has been crafted to create the illusion that modern versions of Windows still use the same basic drive letter conventions as DOS did 40 years ago. I wonder if we'll ever reach a point where Windows no longer uses drive letters, or if it's possible today to somehow remove or disable these abstractions entirely, and run Windows NT without drive letters, as Cutler surely intended. Vast swaths of Windows programs would surely curl up in fetal position and die, including many core components of the operating system itself - as this article demonstrates, very few parts of Windows can handle even something as mundane as a drive letter outside of A-Z - but it'd make for a great experiment. Someone with just the right set of Windows NT skills must've tried something like this at some point, either publicly or inside of Microsoft.

01 Dec 2025 9:06pm GMT

What do you do if you develop a lightweight browser that doesn't support JavaScript, but you once chose GitHub as the home for your code? You're now in the unenviable position that your own browser can no longer access your own online source repository because it requires JavaScript, which is both annoying and, well, a little awkward. The solution is, of course, obvious: you move somewhere else. That's exactly what the Dillo browser did. They set up a small VPS, opted for cgit as the git frontend for its performance and small size, and for the bug tracker, they created a brand new, very simple bug tracker. To avoid this problem, I created my own bug tracker software, buggy, which is a very simple C tool that parses plain Markdown files and creates a single HTML page for each bug. All bugs are stored in a git repository and a git hook regenerates the bug pages and the index on each new commit. As it is simply plain text, I can edit the bugs locally and only push them to the remote when I have Internet back, so it works nice offline. Also, as the output is just an static HTML site, I don't need to worry about having any vulnerabilities in my code, as it will only run at build time. ↫ Rodrigo Arias Mallo There's more considerations detailed in the article about Dillo's migration, and it can serve as inspiration for anyone else running a small open source project who wishes to leave GitHub behind. With GitHub's continuing to add more and more complexity and "AI" to separate open source code from its licensing terms, we may see more and more projects giving GitHub the finger.

01 Dec 2025 8:04pm GMT

Over the course of 2025, every single major cloud provider has failed. In June, Google Cloud had issues taking down Cloud Storage for many users. In late October, Amazon Web Services had a massive outage in their main hub, us-east-1, affecting many services as well as some people's beds. A little over a week later Microsoft Azure had a [widespread outage][Azure outage] that managed to significantly disrupt train service in the Netherlands, and probably also things that matter. Now last week, Cloudflare takes down large swaths of the internet in a way that causes non-tech people to learn Cloudflare exists. And every single time, people share that one XKCD comic.

24 Nov 2025 12:00am GMT

After Gandi was bought up and started taking extortion level prices for their domains I've been looking for an excuse to migrate registrar. Last week I decided to bite the bullet and move to Porkbun as I have another domain renewal coming up. However after setting up an account and paying for the transfer for 4 domains, I realized their DNS services are provided by Cloudflare! I personally do not use Cloudflare, and stay far away from all of their products for various reasons.

18 Nov 2025 12:00am GMT

The waydroid package prior to version 1.5.4-2 (including aur/waydroid) creates Python byte-code files (.pyc) at runtime which were untracked by pacman. This issue has been fixed in 1.5.4-3, where byte-compiling these files is now done during the packaging process. As a result, the upgrade may conflict with the unowned files created in previous versions. If you encounter errors like the following during the update:

error: failed to commit transaction (conflicting files) waydroid: /usr/lib/waydroid/tools/__pycache__/__init__.cpython-313.pyc exists in filesystem waydroid: /usr/lib/waydroid/tools/actions/__pycache__/__init__.cpython-313.pyc exists in filesystem waydroid: /usr/lib/waydroid/tools/actions/__pycache__/app_manager.cpython-313.pyc exists in filesystem

You can safely overwrite these files by running the following command: pacman -Syu --overwrite /usr/lib/waydroid/tools/\*__pycache__/\*

06 Nov 2025 12:00am GMT