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An anonymous reader quotes a report from The Guardian: Miniature human organs and other tissues are to be grown from NHS patients' cells in a drive to improve medicine testing and reduce the number of animals used in drug development. Scientists will use the clumps of tissue to learn how diseases vary between patients, helping them identify which treatments are best for different people based on the particular pathology underlying their condition. The move marks a shift away from the traditional use of animals as models for human disease, towards what researchers believe will be more accurate and reliable tests based directly on human tissues. Researchers have been growing tiny clumps of human organs, known as organoids, for more than a decade. Tests show that pieces smaller than a millimeter can mirror key features of full-scale organs and tissues, including how they falter with disease and respond to drugs. Armed with organoids grown from diseased human tissues, scientists can investigate whether new drug candidates reverse pathological changes in all or a subset of patients, and quickly identify ineffective drugs early in the process. Historically, more than 90% of drugs that clear animal testing go on to fail in human trials, raising questions about the value of the tests. US and European medicines regulators now encourage other approaches if available. "It's going to have a major impact on the numbers of animals used and the way we develop new drugs in the future," said Matthias Zilbauer, a clinical professor of paediatric gastroenterology at the Cambridge Stem Cell Institute. "We're not saying there won't be any animal use in the near or foreseeable future, because there are still certain issues that cannot be tested in these new models, but the reduction is very real." "A lot of human diseases either do not occur in animals or occur in a different way because they're not human," added Zilbauer. "We want tests and models that can tell us which treatments work, and in what patients, and a mouse cannot tell us that."

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14 Aug 2026 3:30am GMT

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14 Aug 2026 2:39am GMT

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14 Aug 2026 12:14am GMT

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14 Aug 2026 12:10am GMT

Microsoft has been steadily scaling back its China presence, closing at least 15 branch offices and joint ventures over the past five years as Beijing favors domestic software. U.S. export controls also make it harder to grow its cloud and AI businesses, leaving the market with relatively little economic upside. Reuters reports: Microsoft took a major hit from the erosion of trust between Washington and Beijing, the five people said. China has since 2017 pushed the use of domestic software, which Beijing sees as more secure and whose quality is increasingly competitive with Windows and Office. U.S. restrictions, including export controls on advanced technology, have meanwhile hindered efforts to scale Microsoft's lucrative AI and cloud businesses in China. [...] Microsoft ultimately decided to remain because it had carved out a profitable business servicing Chinese companies like TikTok owner ByteDance, which need Western technology to manage overseas operations, according to three people familiar with the matter. The company also believed that it needed a presence to maintain access to China's world-class engineering talent, two of them said. Microsoft had also cultivated a relationship with the government that is among the deepest of any tech company, its former China head Alain Crozier told Reuters. "Because of the geopolitics ... some days it's a little bit harder, but we never had a crisis," he said. A Microsoft spokesperson did not address questions about the firm's deliberations on its China business but said it operates in a regulatory "environment that applies to every international supplier" and that it remains committed to the Chinese market. The state of Microsoft's China business reflects market competition, regulatory demands and technological trends, the company said.

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13 Aug 2026 11:00pm GMT

Study finds wait times for cancer surgeries hit 10-year high.

13 Aug 2026 10:17pm GMT

Google has released Gemini 3.7 Flash just three weeks after 3.6 Flash, focusing on better coding, agentic workflows, and enterprise automation while temporarily cutting API prices in half through the end of 2026. VentureBeat reports: For enterprise developers, the more consequential story may be the combination of those intelligence gains with lower inference costs: through the end of 2026, Gemini 3.7 Flash costs $0.75 per million input tokens and $3.75 per million output tokens. Starting Jan. 1, 2027, pricing rises to $1.50 per million input tokens and $7.50 per million output tokens. That means the current discount is temporary, but it gives teams deploying high-volume coding and business agents several months to evaluate whether Google's claimed reductions in retries and manual oversight translate into lower total operating costs. The launch also underscores Google's rapid iteration on its Flash line while its next flagship Pro model remains absent. [...] Google describes Gemini 3.7 Flash as its "most intelligent workhorse model yet for coding and agents." The company says the model is better at adapting when it encounters roadblocks, clarifying intent when necessary and following instructions with greater fidelity. [...] Google's benchmarks show a large generational improvement in several software engineering tests. [...] Google's own results do not show 3.7 Flash universally displacing higher-priced competitors. They instead suggest a model that has become substantially more competitive in coding and agent workloads while occupying a lower price tier.

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13 Aug 2026 10:00pm GMT

Trump memo is first time gov't has authorized private sector to perform cyberattacks.

13 Aug 2026 7:38pm GMT

The new Bullet-Proof KDE Initiative will keep Plasma 6.6 and related KDE components maintained for three years.

13 Aug 2026 7:26pm GMT

Will it be the VSS... Horizon, Explorer, Ascend or Apeiron?

13 Aug 2026 7:12pm GMT

Nitrux unveils its new modular Workspace Environment built around Hyprland, QML, and MauiKit, while officially retiring the Maui Shell project.

13 Aug 2026 6:34pm GMT

Rsync 3.5 is now available with 33 security fixes, including a critical vulnerability, plus extensive hardening across daemon and path handling.

13 Aug 2026 1:57pm GMT