10 Nov 2026

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Ultorg: The User Interface for Relational Databases

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10 Nov 2026 3:59am GMT

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FDA Warns GLP-1s May Increase Risk of Sudden Blindness

An anonymous reader quotes a report from NBC News: The Food and Drug Administration said Monday that GLP-1 drugmakers must add a warning label about a rare eye condition that can cause sudden blindness. The condition, called nonarteritic anterior ischemic optic neuropathy, or NAION, affects the optic nerve, which carries signals from the eye to the brain. When blood flow to the nerve is reduced or blocked, it can cause sudden vision loss. The condition is permanent with no known treatment. The FDA said "there is a potential increased risk of rare NAION" in people taking GLP-1 drugs. The agency's requirement applies to all GLP-1s, including Novo Nordisk's Ozempic and Wegovy and Eli Lilly's Mounjaro and Zepbound, as well as several older GLP-1 diabetes medications. [...] Previous research has found that GLP-1 use may increase the risk of NAION, and Lilly has said it was aware of studies on the potential link. The FDA said it began looking into a possible link after a 2024 study published in JAMA Ophthalmology that found diabetes patients prescribed semaglutide were four times as likely to develop NAION as those not prescribed the drug. The agency said it reviewed reports of side effects submitted to its adverse event monitoring system and analyzed data from multiple clinical trials. Cases of NAION have been reported for all currently marketed GLP-1 drugs, the FDA found. However, FDA scientists were not able to identify a mechanism for how the drugs could increase the risk of the eye condition. Risk factors for NAION can overlap with conditions seen in people taking GLP-1 drugs, including Type 2 diabetes, obesity, sleep apnea and hypertension. "Patients and caregivers should be aware of a potential increased risk of NAION, a rare condition that can result in acute, painless, decreased vision in one eye, including permanent vision loss," with GLP-1 use, the FDA said in the release.

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10 Nov 2026 3:30am GMT

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CoreWeave bond yield tops 16% as AI credit stress rises

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10 Nov 2026 3:20am GMT

Formalizing CPython

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10 Nov 2026 1:56am GMT

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Microsoft Took 31 Years to Let You Kill Windows 11's Sticky Keys Popup

Microsoft is testing a Windows 11 option that lets users permanently disable the Sticky Keys and Filter Keys activation prompts directly from the pop-ups themselves, ending a 31-year-old annoyance without requiring a trip into Settings. Windows Latest reports: Sadly, the dialog is still the same aging Win32 window, but we spotted Microsoft's design boss replying under an X post reply about this, saying he is working on modernizing legacy dialogs. The popup might be annoying, but did you know that it exists because of a pinball game from 1995? [...] The change is in Build 26340.9882 (Experimental) and Build 26320.9876 (Beta), both released on November 6 and based on Windows 11 version 26H2. Microsoft says you can "choose not to be asked again" from the Sticky Keys and Filter Keys dialogs, but it's a Controlled Feature Rollout in Experimental, so you may not see it yet.

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10 Nov 2026 12:00am GMT

09 Nov 2026

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Trump Backs Nvidia CEO Jensen Huang Amid Chinese Spy Affair Investigation

President Donald Trump says the FBI is investigating Nvidia CEO Jensen Huang's affair with a woman alleged by U.S. intelligence to have gathered information for Beijing. "I know the FBI is looking into it in terms of something else, and I think that he'll be in good shape," Trump said at a White House briefing. The Associated Press reports: Trump suggested the extraordinary step of directly involving himself in a counterintelligence investigation, a sign of his friendly relationship with Huang and the possible geopolitical stakes. "I did speak to him today just to see if he's feeling all right, how you're doing," Trump said. "He said he had absolutely no idea that the person in question was a spy." Trump is slated to meet next week with Chinese leader Xi Jinping in Shenzhen, China, at the Asia-Pacific Economic Cooperation summit, but he was noncommittal about bringing up the situation with Xi. "No, I don't think so," Trump said. "I mean, maybe. I'm sure President XI will ask me about it. I just know Jensen very well. I just think he's a very honorable man." Nvidia has launched its own independent investigation into whether Huang was targeted by a foreign intelligence operation. Meanwhile, China has denied the allegations. "The so-called Chinese spy allegation is unsubstantiated. It is nothing but smears against China," Chinese Foreign Ministry spokesperson Guo Jiakun said during a regular news briefing Monday. Further reading: Commerce Dept. Chip Inquiry Was Halted After Nvidia Intervention

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09 Nov 2026 11:00pm GMT

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DCU shake-up: James Gunn and Peter Safran out post-merger

Producer and former Kevin Feige protege Jeremy Latcham will replace Gunn and Safran.

09 Nov 2026 9:55pm GMT

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Mozilla Firefox 160 Introduces Mini Window, Picture-in-Picture Speed Controls

Firefox 160 Introduces Mini Window, Picture-in-Picture Speed Controls

Firefox 160 adds Mini Window, Picture-in-Picture playback speed controls, on-device speech recognition in 40 languages, and improved MKV support.

09 Nov 2026 9:55pm GMT

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Man who lost $308,000 on sports bets sues Kalshi for offering illegal gambling

Lawsuit demands Kalshi return losses because online betting is illegal in Washington.

09 Nov 2026 9:13pm GMT

A Sam Altman parody offers an amusing lesson in memory management

We verified the RAM numbers are real without sending any emails to OpenAI.

09 Nov 2026 8:49pm GMT

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openSUSE Tumbleweed Prepares to Replace YaST Installer with Agama

openSUSE Tumbleweed Prepares to Replace YaST Installer with Agama

openSUSE Tumbleweed is preparing to adopt the modern Agama installer, replacing its traditional YaST-based installation system.

09 Nov 2026 6:56pm GMT

KDE Plasma 6.9 to Improve Widgets, Panels, and Desktop Customization

KDE Plasma 6.9 to Improve Widgets, Panels, and Desktop Customization

KDE Plasma 6.9 improves desktop widgets, adds customizable OSD positioning, enhances panel behavior, and speeds up Spectacle.

09 Nov 2026 12:45pm GMT