nerd

11 Dec 2025

Slashdot

Sperm Donor With Cancer-Causing Gene Fathered Nearly 200 Children Across Europe

schwit1 shares a report from CBS News: perm from a donor who unknowingly carried a cancer-causing gene has been used to conceive nearly 200 babies across Europe, an investigation by 14 European public service broadcasters, including CBS News' partner network BBC News, has revealed. Some children conceived using the sperm have already died from cancer, and the vast majority of those who inherited the gene will develop cancer in their lifetimes, geneticists said. The man carrying the gene passed screening checks before he became a donor at the European Sperm Bank when he was a student in 2005. His sperm has been used by women trying to conceive for 17 years across multiple countries. The cancer-causing mutation occurred in the donor's TP53 gene -- which prevents cells in the body from turning cancerous -- before his birth, according to the investigation. It causes Li Fraumeni syndrome, which gives affected people a 90% chance of developing cancers, particularly during childhood, as well as breast cancer in later life. Up to 20% of the donor's sperm contained the mutated TP53 gene. Any children conceived with affected sperm will have the dangerous mutation in every cell of their body. The affected donor sperm was discovered when doctors seeing children with cancers linked to sperm donation raised concerns at this year's European Society of Human Genetics. At the time, 23 children with the genetic mutation had been discovered, out of 67 children linked to the donor. Ten of those children with the mutation had already been diagnosed with cancer. Freedom of Information requests submitted by journalists across multiple countries revealed at least 197 children were affected, though it is not known how many inherited the genetic mutation. More affected children could be discovered as more data becomes available.

Linuxiac

Krita 5.2.14 Rolls Out Enhanced Touch Controls and New Color Picker

Krita 5.2.14, a free and open-source digital painting app, delivers the final 5.2 bugfix update with a new circular color picker preview, enhanced touch gestures, and more.

11 Dec 2025 9:14am GMT

Hacker News

The Cost of a Closure in C

Comments

11 Dec 2025 7:21am GMT

Slashdot

NASA Loses Contact With MAVEN Mars Orbiter

NASA has lost contact with its MAVEN Mars orbiter after it passed behind Mars. When it remerged from behind the planet, the spacecraft never resumed communications. SpaceNews reports: MAVEN launched in November 2013 and entered orbit around Mars in September 2014. The spacecraft's primary science mission is to study the planet's upper atmosphere and interactions with the solar wind, including how the atmosphere escapes into space. That is intended to help scientists understand how the planet changes from early in its history, when it had a much thicker atmosphere and was warm enough to support liquid water on its surface. MAVEN additionally serves as a communications relay, using a UHF antenna to link the Curiosity and Perseverance rovers on the Martian surface with the Deep Space Network. NASA's Mars Odyssey and Mars Reconnaissance Orbiter spacecraft also serve as communications relays for the rovers, but are both significantly older than MAVEN. The spacecraft has suffered some technical problems in the past, notably with its inertial measurement units (IMUs) used for navigation. In 2022, MAVEN switched to an "all-stellar" navigation system to minimize the use of the IMUs. MAVEN has enough propellant to maintain its orbit through at least the end of the decade. NASA's fiscal year 2026 budget proposal, though, zeroed out funding for MAVEN, which cost $22.6 million to operate in 2024. MAVEN was one of several missions "operating well past the end of prime mission" the proposal would terminate, despite MAVEN's role as a communications relay.

Hacker News

Incomplete list of mistakes in the design of CSS

Comments

11 Dec 2025 4:20am GMT

Slashdot

ChatGPT Is Apple's Most Downloaded App of 2025

An anonymous reader quotes a report from TechCrunch: Apple on Wednesday released its annual list of the most downloaded apps and games for the year. For the U.S. market, OpenAI's ChatGPT topped the ranks of free iPhone apps (not including games) with the most installs in 2025. The AI app was followed by Threads, Google, TikTok, WhatsApp, Instagram, YouTube, Google Maps, Gmail, and Google's Gemini. ChatGPT made it to No. 4 last year, but the top spot was taken by Chinese shopping app Temu. In 2023, the AI app didn't make the top-10 list despite being released on the iPhone in May 2023 to a strong debut.